Wednesday, November 21, 2007

Happy Thanksgiving!

First off- some good news about Erbitux. It seems that it is proving to be more effective than first expected: Read this


What more can I tell you now?

I dont know. This is the middle of treatments and things are either going to stay the same or they will get worse. When I say worse, I mean, I could be a little more tired as things go on, and have some more side effects to deal with, etc..

One good piece of news I can tell you is that my CEA score, which is a blood test that is used to measure cancer activity, is improved. Although this is debatable as I will explain. A normal CEA level can be between 0 and 5. For smokers, that number can be between 0 and 10. And things are still considered normal. My Original CEA score pre-surgery, was 2. Now midway thru chemo, it is 0.8. So it is an improvement, however, these scores are already considered within the normal range.

The truth is that the CEA can be used as an indicator, and some people show scores of 50 or 100 or even higher, but not all people produce a lot of CEA and therefore, you cant really tell when that is the case. Having a tumor, yet having a score of 2, means it isnt a reliable marker for me, yet having it drop to 0.8 is an improvement of sorts. So lets celebrate.

Other news?

Well it looks like my last day of chemo will be February 1st. That is basically 2 months from now. Sounds like a long time but it will be here before ya know it.

In the meantime I am still doing pretty good. Still working, still working out, still doing Yoga, and also working on music too. I must admit though, a few nights a week I enjoy crashing early-- err.. I mean "resting."

Interesting, I never realized this new word that has crept into conversations moreso these days.. the word "rest" or "Im resting"

Q: "What are you doing?"
A: "I'm resting..."


I never used to hear that word or use it even.. Now it seems funny to say that "on Friday night, I stayed in and rested." Resting. what a concept... Its a verb? I can't believe it..

For the moment, Im just "Slouching and Couching" -- There, you like that?

...come February.. no more resting..

Friday, November 2, 2007

HALF WAY DONE - and a recap...

Im getting my sixth round of chemo right now. Im officially halfway done with the treatments. Im excited... its all downhill from here (knock on wood)

Just to recap and fill in some blanks, here is whats happening..

In the middle of June, I went to an outdoor Doobie Brothers Concert, then two days later the results of a colonoscopy came back and I was diagnosed with Colon Cancer..

While still in shock and disbelief, I immediately emailed my friend Shyam, who is a surgeon with the US Navy, but he was in Iraq saving lives at the time. He helped me by answering my many questions via email and setting me at ease.

I got some scans done and it showed a small 3cm mass in the wall of my colon which appeared to be a Stage I tumor, which is good.

Following that, I met with several surgeons to see what my options were. One was at University of Chicago, and another was at Northwestern Memorial, the top two hospitals in the area.

I went with Dr. Steven Stryker, because he had the most experience and also felt very comfortable doing the surgery as a "Laparoscopically Assisted" procedure which meant smaller incisions and faster recovery time. He actually wrote a very important paper comparing Laparoscopic vs Open Surgery some time ago showing that the two are equally safe procedures.(Here is an abstract on it)The surgery went very well and already my scars from the incisions are fading.

Next I researched on my own, and started on a regimen of alternative medicines including ACHH, to raise the immune system, and Avemar, a substance shown to regulate the white blood cells and fight cancer.

I had surgery on July 12th. A few says later, the pathology report came back showing that this tumor skipped over stage II, and went straight to stage III; 4 out of 21 lymph nodes harvested from surgery contained stray cancer cells. Strong chemo would be necessary.

I had another small outpatient surgery to implant a port in my chest. Basically it looks like this . It rests under the skin below my collar bone and the tube feeds directly into a main artery that goes to the heart. I dont even feel it and all you would see is a slight lump under my skin. It is used as a way to give me chemo rather than constantly pricking a vein in my arm to connect an IV. After these treatments are all done, after a few months to make sure everything is allright, there will be another short surgery to remove it.

Who will be giving me chemo? I again investigated several options. Northwestern's Robert Lurie Cancer Center was one, a local option was another, and another Oncology group located across the street from Northwestern was a third option. After doing my homework, and individually meeting with several Oncologists, I chose Dr John Shaw at Hematology Oncology Associates of Illinois. He came highly recommended and also we seemed to get along the best.

He put me on FOLFOX which is the first-line chemo for Colon Cancer. FOLFOX is an acronym for three drugs. (Folonic Acid, also known as Leucovorin, 5-FU or Fluorouracil, and Oxaliplatin, also called Oxaliplatinum.)

In addition, I got into a Clinical Trial for Erbitux, a very new kind of chemo drug that attacks cancer cells based on a protein that exists on the outer cell wall. This protein is also found in skin cells so it provides a nice rash on my face. Because Im in the study, I was assigned a special Chemo-Dermatologist at Northwestern to basically thwart off skin problems that can develop, so that I will be able to take Erbitux non-stop for the entire length of the treatment. More on this in a future post.

OK.

In addition, I continued biking and rode over 400 miles this summer. Half of that time I was on chemo. Now its too cold to bike so I have to find something else to do. In the interim I have started sleeping more - as in 13 hour stretches. Its obvious that exercise makes a difference, so its time to get moving doing some aerobic exercise.

On Sundays I have been lifting weights with my cousin Daryl, at City Wide Super Slow in order to gain muscle mass and come out of this looking and feeling better than I did before. I have to say that my muscles are looking pretty good these days all things considered... (A more detailed post to follow on this)

Finally, I have also been attending a yoga class on Wednesdays which has been really great for having a peaceful mind, and stretching my body to keep it in shape.

Its all helping.

On top of it, I really appreciate my friends, relatives, and co-workers for being so supportive throughout this ordeal. This is the kind of thing where I could easily feel disconnected and isolated from people in general, but that has not been the case, in fact I feel more of a connection than before, to the people who are close to me, as well as people in general.